Current research and treatment for gastrointestinal stromal tumors

Figure 1 Gastroscopy view of a gastric gastrointestinal stromal tumors. A 4 cm × 4 cm in diameter gastric fundal submucosal tumor with a central ulceration associated with a recent bleed is shown.

Figure 2 Computed tomography scan image of a gastric gastrointestinal stromal tumors. A submucosal tumor measuring 7.7 cm × 7.6 cm × 7.2 cm in dimension was located on the posterior wall of gastric antrum. An ill-defined hypodensity within the mass could represent an area of necrosis.

Figure 3 ¹⁸Fluoro-deoxyglucose-positron emission tomography scan views of a small bowel gastrointestinal stromal tumors. There is a mildly fluoro-deoxyglucose avid mass adjacent to the jejunal anastomosis with SUVmax 3.4 suggestive of a local recurrence.

Figure 4 Endoscopic ultrasonography images of esophageal gastrointestinal stromal tumors. A distal esophageal submucosal lesion measuring 2.6 cm × 1.3 cm in diameter was noted to be well circumscribed, heterogeneous with hypoechoic echotexture without disruption of wall architecture and with no perilesional lymph node.

Figure 5 Endoscopic ultrasound scan and fine needle aspiration image of an esophageal gastrointestinal stromal tumors. The procedure was performed using a 22F procore needle with on-site cytotech.

Figure 6 Macroscopic image of a recurrent small bowel gastrointestinal stromal tumors. A picture of a large enbloc resection specimen of a small bowel mesentery and jejunum was taken along a separate smaller metastatic mesenteric nodule.

Figure 7 Algorithm for the management of gastrointestinal stromal tumors. GIST: Gastrointestinal stromal tumor; CT: Computed tomography; TKI: Tyrosine kinase inhibitor.