Meta-Analysis
Copyright ©The Author(s) 2017.
World J Gastroenterol. Jan 14, 2017; 23(2): 336-344
Published online Jan 14, 2017. doi: 10.3748/wjg.v23.i2.336
Figure 1
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Figure 1 Area under the curve (W0-W8) (A) and area under the curve (W5-W8) (B) of abdominal pain/discomfort in intent to treat population (all irritable bowel syndrome subtypes) and in irritable bowel syndrome-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline (irritable bowel syndrome-C ≥ 2) under placebo (white) or Saccharomyces cerevisiae CNCM I-3856 (grey) supplementation. Significant differences compared to placebo are symbolized by aP < 0.05. IBS-C: Irritable bowel syndrome-C; a.u.: Arbitrary unit; ITT: Intent to treat; AUC: Area under the curve.
Figure 2
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Figure 2 Area under the curve (W0-W8) (A) and area under the curve (W5-W8) (B) of bloating in intent to treat population (all irritable bowel syndrome subtypes) and in irritable bowel syndrome-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline (irritable bowel syndrome-C ≥ 2) under placebo (white) or Saccharomyces cerevisiae CNCM I-3856 (grey) supplementation. aP < 0.05, Significant differences, vs placebo are symbolized. IBS-C: Irritable bowel syndrome-C; a.u.: Arbitrary unit; ITT: Intent to treat; AUC: Area under the curve.
Figure 3
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Figure 3 Evolution of stool consistency in irritable bowel syndrome-C subjects during the 8-wk supplementation with active product (Saccharomyces cerevisiae CNCM I-3856, white squares) or placebo product (black circles). Values are estimated means, with standard error represented by vertical bars. aP < 0.05, bP < 0.01, Significant differences, vs placebo are symbolized. IBS-C: Irritable bowel syndrome-C; a.u.: Arbitrary unit.
Figure 4
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Figure 4 Evolution of stool consistency in irritable bowel syndrome-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline (irritable bowel syndrome-C ≥ 2) during the 8-wk supplementation with active product (Saccharomyces cerevisiae CNCM I-3856, white squares) or placebo product (black circles). Values are estimated means, with standard error represented by vertical bars. aP < 0.05, bP < 0.01, Significant differences, vs placebo are symbolized. IBS-C: Irritable bowel syndrome-C; a.u.: Arbitrary unit.