Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective

doi:10.3748/wjg.v22.i33.7463

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2016; 22(33): 7463-7477
Published online Sep 7, 2016. doi: 10.3748/wjg.v22.i33.7463

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Figure 1 Bile acids are in the central position of oncogenic and metabolic pathways. MMP: Matrix metalloproteinase; FXR: Farnesoid X nuclear receptor; TGR5: Takeda G-protein receptor 5.

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Figure 2 Bile acids metabolism. FXR: Farnesoid X nuclear receptor; DCA: Deoxycholic acid; LCA: Lithocholic acid; CDCA: Chenodeoxycholic acid; CA: Cholic acid.

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Figure 3 Oncogenic process of bile acid reflux.

Citation: Feng HY, Chen YC. Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective. World J Gastroenterol 2016; 22(33): 7463-7477
URL: https://www.wjgnet.com/1007-9327/full/v22/i33/7463.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i33.7463