Biomarkers of skin toxicity induced by anti-epidermal growth factor receptor antibody treatment in colorectal cancer

doi:10.3748/wjg.v22.i2.887

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2016; 22(2): 887-894
Published online Jan 14, 2016. doi: 10.3748/wjg.v22.i2.887

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Figure 1 Homeostasis and epidermal growth factor receptor downstream signaling pathway in keratinocyte. EGFR: Epidermal growth factor receptor; TGF-α: Transforming growth factor-alpha; AREG: Amphiregulin; HB-EGF: Heparin-binding epithelial growth factor.

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Figure 2 Schema of EVEREST II trial (a non-randomized phase II study). FOLFIRI: 5-fluorouracil/leucovorin/irinotecan.

Citation: Kubo A, Hashimoto H, Takahashi N, Yamada Y. Biomarkers of skin toxicity induced by anti-epidermal growth factor receptor antibody treatment in colorectal cancer. World J Gastroenterol 2016; 22(2): 887-894
URL: https://www.wjgnet.com/1007-9327/full/v22/i2/887.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i2.887