Missing metastases as a model to challenge current therapeutic algorithms in colorectal liver metastases

Figure 1 Rates of local recurrence of non-resected missing liver metastases according to the time of reporting. Local recurrence rates of unresected MLM according to the time of reporting, in 6 studies in which the in situ recurrence rates of MLM left in place could be calculated, in 2006[40], 2007[41], 2009[42], 2010[43], 2011[44] and 2012[47].

Figure 2 Therapeutic strategy in patients with patients with colorectal liver metastases. The potential role for adjuvant surgery. CEA: Carcinoembryonic antigen; MLM: Missing liver metastase; HAI: Hepatic arterial infusion of chemotherapy; LM: Liver metastases.