Primary splenic angiosarcoma with liver metastasis: A case report and literature review

Figure 1 Magnetic resonance imaging. A: Coronal T2-weighted image revealed multiple nodular lesions in the liver parenchyma; B: Contrast-enhanced magnetic resonance imaging showed marked heterogeneous enhancement in the splenic mass, and multiple high signal intensity lesions in the liver.

Figure 2 Histopathologic findings of the splenic specimen. Clusters of spindle tumor cells infiltrating the spleen parenchyma (HE stain; magnification × 200).

Figure 3 Immunohistochemical examination of the splenic specimen. A: Specimen stained positive for CD31 (magnification × 200); B: Specimen stained positive for CD34 (magnification × 200); C: Specimen stained positive for FVIII (magnification × 200); D: Ki-67 proliferation index less than 30% (magnification × 100).