Hepatitis B virus and hepatitis C virus play different prognostic roles in intrahepatic cholangiocarcinoma: A meta-analysis

Figure 1 Flowchart of the literature search strategy. HBV: Hepatitis B virus; HCV: Hepatitis C virus; OS: Overall survival; DFS: Disease-free survival.

Figure 2 Forest plot of the hazard ratio for the association of hepatitis B virus infection and survival. The survival data are reported as overall survival and disease-free survival.

Figure 3 Forest plot of the hazard ratio for the association between hepatitis C virus infection and survival. The prognostic information is reported as overall survival.

Figure 4 Forest plots of the hazard ratio for the association of hepatitis B virus infection with overall survival by subgroup analysis. A: By sample size; B: By tumor type; C: By study region; D: By mean age.

Figure 5 Forest plots of odds ratios for the association of hepatitis B virus infection with clinicopathological features. A: Meta-analysis for gender; B: Meta-analysis for AST levels; C: Meta-analysis for AFP levels; D: Meta-analysis for CA19-9 levels; E: Meta-analysis for cirrhosis; F: Meta-analysis for capsule formation; G: Meta-analysis for lymph node metastasis.

Figure 6 Funnel plots of the studies included in the meta-analysis. Hepatitis B virus and overall survival (OS); B: Hepatitis C virus and OS.