Castleman’s disease of the spleen

Figure 1 Computed tomography of the abdomen and pelvis shows a 5. 7 cm × 4.5 cm sized solid mass in the spleen.

Figure 2 A specimen obtained during splenectomy.

Figure 3 Castleman’s disease. A: In a low-power field (magnification × 100), enlarged follicles with atrophic centers and pale pink vessels rich in interfollicular stroma are observed; B: In a high-power field (magnification × 400), hyaline deposition in the germinal center and expanded mantle zones of concentric small lymphocytes are observed.