Oncogenic role of p21 in hepatocarcinogenesis suggests a new treatment strategy

doi:10.3748/wjg.v21.i42.12150

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Nov 14, 2015 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2015; 21(42): 12150-12156
Published online Nov 14, 2015. doi: 10.3748/wjg.v21.i42.12150

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Figure 1 Outline of the overall aspects of this review. The subcellular localization of p21 and other tumor suppressors is regulated by CRM1. Inhibition of CRM1 by specific inhibitors and IFN may play a role in future anti-hepatocellular carcinoma strategies. CRM1: Chromosome region maintenance 1; IFN: Interferon; SINE: Selective inhibitors of nuclear export.

Citation: Ohkoshi S, Yano M, Matsuda Y. Oncogenic role of p21 in hepatocarcinogenesis suggests a new treatment strategy. World J Gastroenterol 2015; 21(42): 12150-12156
URL: https://www.wjgnet.com/1007-9327/full/v21/i42/12150.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i42.12150