Gastric adenocarcinoma of fundic gland type: Five cases treated with endoscopic resection

Figure 1 Endoscopic examination of five cases. A: Conventional white light endoscopy showed elevated (type 0-IIa) or flat (type 0-IIb) lesions with dilatation of microvessels on the upper gastric body; B: Narrow-band imaging with magnifying endoscopy showed an irregular microvascular pattern (MVP) and an absent microsurface pattern (MSP) on the small region of the tumor in cases 1 and 2, while regular MVP and MSP were demonstrated in the remainder.

Figure 2 Pathological examination of resected gastric adenocarcinoma of fundic gland type (case 1). A: In low-power view, the tumor arose from the deep layer of the lamina propria mucosae and invaded the submucosal layer at a depth of 980 μm (arrow). Most of the surface was covered with non-atypical foveolar epithelium; B: In high-power view, the tumor was composed of well-differentiated columnar cells mimicking the fundic gland cells with mild nuclear atypism; C: Immunohistological staining showed diffuse positivity for pepsinogen-I.