Molecular aspects of intestinal calcium absorption

doi:10.3748/wjg.v21.i23.7142

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Jun 21, 2015 (publication date) through Jul 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2015; 21(23): 7142-7154
Published online Jun 21, 2015. doi: 10.3748/wjg.v21.i23.7142

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Figure 1 Schematic representation of intestinal Ca²⁺ absorption. ADP: Adenosine monophosphate; ATP: Adenosine triphosphate; Cldns: Claudins; NCX1: Intestinal Na⁺/Ca²⁺ exchanger; PMCA1b: Plasma membrane Ca²⁺- ATPase 1b; TJ: Tight junctions; TRPV6: Transient receptor potential vanilloid 6; TRPV5: Transient receptor potential vanilloid 5; VDR: Vitamin D receptor; 1,25(OH)₂D₃: Calcitriol.

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Figure 2 Hormonal regulation of intestinal calcium absorption. CB: Calbindin; Cldn: Claudin; GC: Glucocorticoids; GH: Growth hormone; IGF1: Insulin-like growth factor 1; NCX1: Intestinal Na⁺/Ca²⁺ exchanger; PI3K: Phosphoinositide 3-kinase C; PKC: Protein kinase C; PMCA1b: Plasma membrane Ca²⁺- ATPase 1b; PRL: Prolactin; PTH: Parathyroid hormone; ROCK: RhoA-associated coiled-coil-forming kinase; TH: Thyroid hormones; TRPV6: Transient receptor potential vanilloid 6.

Citation: Diaz de Barboza G, Guizzardi S, Tolosa de Talamoni N. Molecular aspects of intestinal calcium absorption. World J Gastroenterol 2015; 21(23): 7142-7154
URL: https://www.wjgnet.com/1007-9327/full/v21/i23/7142.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i23.7142