Expression of COX-2 and HER-2 in colorectal cancer and their correlation

Figure 1 Immunohistochemical staining of COX-2 and HER-2 in colorectal cancer and normal colorectal tissue. A: COX-2-positive expression in colorectal cancer, magnification × 200; B: HER-2 positive expression in colorectal cancer, magnification × 200; C: COX-2-negative expression in normal colorectal tissue, magnification × 100; D: HER-2-negative expression in normal colorectal tissue, magnification × 100.

Figure 2 Survival curves for patients with colorectal cancer. A: Patients with positive and negative COX-2 expression; B: Patients with positive and negative HER-2 expression.

Figure 3 Survival curves of colorectal cancer patients positive for both COX-2 and HER-2, positive for either of them, and negative for both. Compared with patients positive for both markers, patients negative for both had better survival.