Methyl-methanesulfonate sensitivity 19 expression is associated with metastasis and chemoradiotherapy response in esophageal cancer

Figure 1 Methyl-methanesulfonate sensitivity 19 immunohistochemistry. Normal esophageal squamous epithelium with A: Strong nuclear but weak cytoplasmic staining; B: Strong cytoplasmic staining in the basal and suprabasal layers, with scattered strong nuclear staining in the normal epithelium area; C: Weak staining in both the cytoplasm and nucleus (Magnification × 200); Esophageal squamous cell carcinoma with D: Strong staining in the cytoplasm and nucleus; E: Strong staining in the cytoplasm and weak staining in the nucleus; F: Weak staining in both the cytoplasm and nucleus (Magnification × 400).