Parameters of a severe disease course in ulcerative colitis

Figure 1 Representation of the number of immunosuppressive drugs per patient during follow-up.

Figure 2 Statistically different necessity of immunosuppressive treatment in the course of the disease depending on response to steroid therapy.

Figure 3 Results of our model to calculate the individual probability of immunosuppressive treatment depending on the identified risk factors; representation of three hypothetical patients. Right handside: Percentage of patients with a probability to require immunosuppressive treatment (IT) no more than 20%, at least 80% and at least 90%, respectively (Patient #1: female; 19 years at diagnosis; pancolitis; hospitalisation and steroids at diagnosis, steroid-refractory; Patient #2: male; 28 years at diagnosis, left-sided colitis; hospitalisation and steroids at diagnosis; remission; Patient #3: male; 47 years at diagnosis; proctitis; no hospitalisation and no steroids at diagnosis).