Colorectal cancer with liver metastases: Neoadjuvant chemotherapy, surgical resection first or palliation alone?

Figure 1 The treatment options for colorectal liver-only metastases. MDT: Multi-disciplinary team; CT: Computed tomography; PET: Positron emission tomography; MRI: Magnetic resonance imaging; VEGF: Vascular endothelial growth factor; EGFR: Epidermal growth factor receptor; PD: Progressive disease; SD: Stable disease; PR: Partial response.

Figure 2 Computed tomography images. A: Computed tomography (CT) scan of a patient showing extensive liver metastatic disease prior to systemic therapy; B: CT scan after 4 cycles of neo-adjuvant chemotherapy demonstrating excellent partial response to the treatment along with intra-tumoural calcification; C: CT scan following left hepatectomy.