Effectiveness of nonsteroidal anti-inflammatory drugs in prevention of post-ERCP pancreatitis: A meta-analysis

Figure 1 Schematic representation of the article screening process. RCP: Rretrograde cholangiopancreatography; NSAID: Nonsteroidal anti-inflammatory drug; PEP: Post-endoscopic retrograde cholangiopancreatography pancreatitis.

Figure 2 Meta-analysis of the effect of prophylactic nonsteroidal anti-inflammatory drug administration on post-endoscopic retrograde cholangiopancreatography pancreatitis incidence. A fixed-effect model was applied to this pooled meta-analysis, which included eight articles, to analyze the effect of prophylactic nonsteroidal anti-inflammatory drug (NSAID) administration on post-endoscopic retrograde cholangiopancreatography pancreatitis incidence.

Figure 3 Meta-analysis of the effect of nonsteroidal anti-inflammatory drug administration on mild pancreatitis post endoscopic retrograde cholangiopancreatography. Subgroup-analysis, which included six articles with a fixed-effect model, was performed to analyze the effect of prophylactic nonsteroidal anti-inflammatory drug (NSAID) administration on the incidence of mild pancreatitis.

Figure 4 Meta-analysis of the effect of nonsteroidal anti-inflammatory drug administration on moderate to severe pancreatitis post endoscopic retrograde cholangiopancreatography. Subgroup-analysis, which included five articles with a fixed-effect model, was performed to analyze the effect of prophylactic nonsteroidal anti-inflammatory drug (NSAID) administration on the incidence of moderate to severe pancreatitis.

Figure 5 Funnel plot to evaluate the effect of nonsteroidal anti-inflammatory drug administration on post-endoscopic retrograde cholangiopancreatography pancreatitis.