Two cases of neuroendocrine carcinoma of the gallbladder

Figure 1 Computed tomography scan of the gallbladder carcinoma. A: A thick-walled gallbladder with local infiltration to the adjacent liver; B: A polypoid intra-luminal lesion about 4 cm in diameter.

Figure 2 Pathological examination, HE, × 400. A: Postoperative pathological findings were poorly differentiated neuroendocrine carcinoma with serosal invasion and liver invasion; B: No transitional areas were observed between the two different parts.

Figure 3 Immunohistochemical staining for chromogranin A. A: Immunohistochemical staining revealed positive expression of chromogranin A (CGA); B: Immunohistochemically, the tumor was positive for CGA.

Figure 4 Immunohistochemical staining for synaptophysin. A: Immunohistochemical staining revealed positive expression of synaptophysin (SYN); B: Immunohistochemically, the tumor was positive for SYN.