Solitary rectal ulcer syndrome: Clinical features, pathophysiology, diagnosis and treatment strategies

Figure 1 Endoscopic imaging and corresponding histological findings in solitary rectal ulcer syndrome patients. A: Colonoscopy revealed localized yellowish slough, rectal edema, erythema, and superficial ulcerations; B: Histology (hematoxylin and eosin) shows smooth muscle hyperplasia in the lamina propria between colonic glands, and surface ulceration with associated chronic inflammatory infiltrates. Magnification: × 40 (left), × 100 (right).

Figure 2 Suggested algorithm for treatment strategies in patients with solitary rectal ulcer syndrome. SRUS: Solitary rectal ulcer syndrome.