Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis: Systematic review and meta-analysis

Figure 1 Flow chart illustrating summary of literature search results.

Figure 2 Forest plot comparing tumour margins following open and laparoscopic approaches, standard mean difference with 95%CI, P = 0. 011. I² measure of heterogeneity 0.0%, P = 0.631. SMD: Standard mean differences.

Figure 3 Forest plot comparing blood loss following open and laparoscopic approaches, standard mean difference with 95%CI, P < 0. 001. I² measure of heterogeneity 96.2%, P < 0.001. SMD: Standard mean differences.

Figure 4 Forest plot comparing relative risk of blood transfusions following open and laparoscopic approaches, 95%CI, P < 0. 001. I² measure of heterogeneity 0.0%, P = 0.845.

Figure 5 Forest plot comparing standard mean difference of operative times following open and laparoscopic approaches, with 95%CI, P = 0. 142. I² measure of heterogeneity 24.2%, P = 0.266. SMD: Standard mean differences.

Figure 6 Forest plot comparing relative risk of post-operative morbidity following open and laparoscopic approaches, with 95%CI, P < 0. 001. I² measure of heterogeneity 41.1%, P = 0.165.

Figure 7 Forest plot comparing standard mean difference of length of stay following open and laparoscopic approaches, with 95%CI, P < 0. 001. I² measure of heterogeneity 59.8%, P = 0.058. SMD: Standard mean differences.