Use of lectin microarray to differentiate gastric cancer from gastric ulcer

Figure 1 Sugar-binding specificities of the lectins and the layout of the lectin microarray.

Figure 2 Glycopatterns of gastric cancer and ulcer according to lectin microarrays. After scanning of MPL and VVA lectins, a diagram was shown.

Figure 3 Level of GalNAc bound by MPL in various types of gastric cancer and gastric ulcer. A: Staining of adenocarcinoma (× 400); B: Staining of signet ring cell carcinoma (× 400); C: Staining of undifferentiated carcinoma (× 400); D: Staining of carcinoid (× 400); E: Staining of lymphatic metastatic adenocarcinoma (× 400); F: Staining of intra-mucosal carcinoma (× 400); G: Staining of gastric ulcer (× 400).

Figure 4 Level of GalNAc bound by VVA in various types of gastric cancer and gastric ulcer. A: Staining of adenocarcinoma (× 400); B: Staining of signet ring cell carcinoma (× 400); C: Staining of undifferentiated carcinoma (× 400); D: Staining of carcinoid (× 400); E: Staining of lymphatic metastatic adenocarcinoma (× 400); F: Staining of intra-mucosal carcinoma (× 400); G: Staining of gastric ulcer (× 400).

Figure 5 Pathological score of tissue staining. The figure compares gastric ulcer and various types of gastric cancer. A indicates MPL, and B represents VVA. ^aP < 0.05, ^bP < 0.01, ^dP < 0.01.