Inflammatory bowel disease and celiac disease: Overlaps and differences

Figure 1 Immunopathology. Overlap between inflammatory bowel disease (IBD) [considering the two major forms Crohn’s disease (CD) and ulcerative colitis (UC)] and celiac disease (CeD) for the loci identified by large scale genetic studies. Genes are grouped according to their participation in three main functional blocks: innate immunity, adaptive immunity, and intestinal barrier. All the genes with still unknown function are grouped as “others”. Note that some genes can be found in more than one functional group.