Serrated pathway in colorectal carcinogenesis

Figure 1 Hematoxylin and eosin of representative cases of serrated lesions. A: Microvesicular hyperplastic polyp (× 100); B: Goblet cell hyperplastic polyp (× 100); C: Sessile serrated adenomas (× 100); D: Traditional serrated adenomas (× 100).

Figure 2 Schematic view of serrated polyps: Carcinoma sequence. MVHP: Microvesicular hyperplastic polyp; GCHP: Globet cell hyperplastic polyp; MPHP: Mucin-poor hyperplastic polyp; SSA: Sessile serrated adenoma; TSA: Traditional serrated adenoma; MP: Mixed polyp; MSI-H: High microsatellite instability; CIMP: CpG island methylator phenotype.