Magnifying endoscopy for the diagnosis of specialized intestinal metaplasia in short-segment Barrett’s esophagus

Figure 1 Screening endoscopy. A-C: Endoscopically suspected short-segment Barrett’s esophagus (< 3 cm).

Figure 2 Magnifying endoscopy. A: Magnifying endoscopy up to × 80 (Olympus GIF-Q240Z, × 80); B: Magnified image of the short-segment Barrett’s esophagus.

Figure 3 Classification of pit-pattern of Barrett’s esophagus by Magnifying endoscopy (Endo’s classification). A:I (small round); B: II (straight); C: III (long oval); D: IV (tubular); E: V (villous).

Figure 4 Methylene blue chromoendoscopy. A: 0.5% solution of methylene blue (MB) was sprayed over the columnar mucosa; B: Biopsies were obtained from the regions previously observed by magnifying endoscopy and MB chromoendoscopy.

Figure 5 Histological diagnosis. A: Fundic type (HE stain, × 200); B: Cardiac type (HE stain, × 200); C: Specialized intestinal metaplasia (HE stain, × 400).

Figure 6 Distributions of pit-pattern, methylene blue staining, histologic diagnosis. A: Pit-pattern; B: Methylene blue staining; C: Histologic diagnosis. SIM: Specialized intestinal metaplasia.