Krüppel-like factor 8 overexpression is correlated with angiogenesis and poor prognosis in gastric cancer

Figure 1 Immunohistochemical staining of Krüppel-like factor 8 and CD34 in gastric cancer specimens. A: Negative expression of Krüppel-like factor 8 (KLF8) in cancer cells; B: Weakly positive expression of KLF8 in cancer cells; C: Strongly positive expression of KLF8 in cancer cells; Magnification: × 400; D: Intratumoral microvessels detected by anti-CD34 antibody (brown) in gastric cancer tissues; Magnification: × 200.

Figure 2 Kaplan-Meier survival curves of overall and cancer-specific survival in gastric cancer patients based on Krüppel-like factor 8 expression. Patients with Krüppel-like factor 8 (KLF8)-positive (weakly and strongly) expression had poorer overall (A) and cancer-specific (B) survival as compared to those with KLF8-negative expression.