Gene expression profiles in peripheral blood mononuclear cells of ulcerative colitis patients

Figure 1 High-enrichment gene ontology represented by differentially expressed genes. A P < 0.01 in the Fisher’s exact test was selected as the significance criterion. Over-expressed genes were mainly segregated to three critical biological processes: immune and inflammatory response, cell cycle and proliferation, DNA metabolism and repair. JAK-STAT: Janus kinase-signal transducer and activator of transcription.

Figure 2 Semiquantitative relative reverse transcription-polymerase chain reaction validation of 6 selected genes. The values were normalized against β-actin. Graph bars indicate the averaged absorbance (A) ratios between each gene and β-actin. Values represent the mean ± SE. Significance levels were: ^aP < 0.05, ^bP < 0.01 vs control subjects. UC: Ulcerative colitis.