Infliximab induces remission in cryptogenic multifocal ulcerous stenosing enteritis: First case

Figure 1 Computed tomography showing the location of a potential short stricture (arrow) in the preterminal ileum with mild pre- and poststenotic dilatation. This stricture was identified only after second reading of the computed tomography images and based upon the enteroscopic findings. A: Transverse plane; B: Coronal plane; C: Parasagittal plane.

Figure 2 High definition endoscopic image of a circular ulcerative stenosis in the ileum, 50 cm proximal from the ileocecal valve. After infliximab induction therapy, the ulceration almost completely disappeared and only a short hyperemic and less pronounced stenosis remained. A: Before infliximab; B: After infliximab.

Figure 3 Ileal biopsy before and after infliximab treatment. A: Superficial ulceration of the mucosa (arrow), with an acute inflammatory infiltrate in the lamina propria (HE stained paraffin section, bar: 100 μm); B: Ileal biopsy after treatment with infliximab, showing restoration of the villus architecture and only slight, non-specific inflammatory changes (bar: 200 μm).