Comparative effectiveness of i-SCAN™ and high-definition white light characterizing small colonic polyps

Figure 1 Correct prediction of small colonic polyps. A: Correctly predicted as hyperplastic, visualized under high-definition white light; B: Correctly predicted as hyperplastic, visualized under i-SCAN; C: Pathology demonstrating colonic mucosa with serrated architecture extending midway down the glands and non-dysplastic cytology, consistent with a hyperplastic polyp [hematoxylin and eosin (HE); 4 ×]; D: Correctly predicted as adenoma, visualized under high-definition white light; E: Correctly predicted as adenoma, visualized under i-SCAN; F: Pathology demonstrating colonic mucosa with hyperchromatic, elongated, and pseudostratified nuclei, consistent with a tubular adenoma (HE; 4 ×).