Reduced Popdc3 expression correlates with high risk and poor survival in patients with gastric cancer

Figure 1 Immunohistochemical staining for Popeye domain containing 3 in gastric cancer lesions and noncancerous tissues. A: Popeye domain containing 3 (Popdc3) was highly expressed in noncancerous tissues, × 400; B: Popdc3 was highly expressed in intestinal metaplasia cells, × 400; C, D: Popdc3 was lowly expressed in tubular adenocarcinoma, × 200 and × 400, respectively.

Figure 2 Kaplan-Meier curves with univariate analyses (log-rank) for patients with low Popeye domain containing 3 expression vs high Popeye domain containing 3 expression tumors in all gastric cancer. The cumulative and 3-year survival rates were 88.46% and 84.6%, respectively in the high Popeye domain containing 3 (Popdc3) protein expression group, but was only 76.75% and 16.7% in the low expression group (χ² = 145.095, P < 0.0001).