Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy

Figure 1 Immunohistochemical staining of full length cytokeratin-18 and caspase-cleaved cytokeratin-18. A: Immunohistochemical staining of full length cytokeratin-18 (CK-18) showing strong cytoplasmic staining; B: Immunohistochemical staining for caspase-cleaved CK-18. Cores from tumour showing positively-stained apoptotic cells. Original magnification × 100; insets × 400.

Figure 2 Kaplan Meier curves representing the relationship between caspase-cleaved cytokeratin-18 and disease-specific survival. A: In months from time of diagnosis in patients who received primary surgery only; B: In patients who received neoadjuvant chemotherapy.