Pancreatic schwannoma: Case report and an updated 30-year review of the literature yielding 47 cases

Figure 1 Contrast-enhanced computed tomography scan obtained in the arterial phase showing a multilocular cystic mass in the uncinate process of the pancreas. No pancreatic ductal dilatation or invasion into adjacent arteries or portal vein are identified.

Figure 2 Intraoperative ultrasound showing the well-encapsulated pancreatic mass that is composed of solid and cystic components.

Figure 3 Microscopic examination demonstrating spindle cells without nuclear atypism (HE x 100). Immunohistochemical staining for S-100 protein was positive. HE: Hematoxylin and eosin.

Figure 4 Analysis for relation between tumor size and malignant potential and tumor nature (solid or cystic) in all 47 cases of pancreatic schwannoma. A: Relationship between tumor size and malignancy. Larger tumor size is related to malignant tumor (13.8 ± 6.2 cm for malignancy vs 5.5 ± 4.4 cm for benign, P = 0.001); B: Relationship between tumor size and nature of tumor. Larger tumor size is related to cystic degeneration (13.8 ± 6.2 cm for cystic tumor vs 5.5 ± 4.4 cm for solid tumor, P = 0.005).