Severe chronic diarrhea and maculopapular rash: A case report

Figure 1 Maculopapular rash (“urticaria pigmentosa”) in a systemic mastocytosis patient.

Figure 2 Abdominal ultrasound. A: Small bowel dilatation and wall edema at ultrasonography (US). B: Abdominal lymphadenopathy at US (crosses refer to lymph node enlargement, 5 cm).

Figure 3 Colon biopsy in a systemic mastocytosis patient. A: Diffuse mast cell (MC) infiltrate (Hematoxylin-eosin, × 10); B: The dense infiltrate is represented by MCs, whose detection is increased by positive immunohistochemical marker CD117; C: The dense infiltrate is represented by MCs, whose detection is increased by positive immunohistochemical marker CD25.

Figure 4 Bone marrow biopsy in a systemic mastocytosis patient. A: Diffuse mast cell (MC) infiltrate (Hematoxylin-eosin, × 10); B: The dense infiltrate is represented by MCs, whose detection is increased by positive immunohistochemical marker CD117; C: The dense infiltrate is represented by MCs, whose detection is increased by positive immunohistochemical marker CD25.