Evaluation of small bowel blood flow in healthy subjects receiving low-dose aspirin

Figure 1 Study design. A randomized placebo-controlled double-blinded cross-over study was performed using rebamipide. Capsule endoscopy and contrast-enhanced ultrasonography were performed before and after administration of drugs.

Figure 2 Image of contrast-enhanced ultrasonography. Regions of interests (ROI) were placed in the mucosal area of the small bowel at three regions. A time intensity curve of blood flow enhancement signal was plotted from recorded ultrasonographic images.

Figure 3 Image of capsule endoscopy. Low-dose aspirin induced mucosal breaks such as denuded areas and erosions were detected in the placebo group. A: Denuded area; B: Erosion.