Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer

Figure 1 Temperature profile of LeGoo-Endo™ (PS137-25) that transits from liquid to gel at body temperature. The viscosity of LeGoo-Endo™ with Lidocaine is slightly higher than LeGoo-Endo™ at body temperature.

Figure 2 Illustration of endoscopic ultrasound (EUS)-guided celiac plexus neurolysis (CPN). Figure from Arcidiacono PG, Rossi M. Celiac Plexus Neurolysis. J Pancreas 2004; 5: 315-321.

Figure 3 EUS-guided injection of Lidocaine plus blue colored poloxamer PS 137-25. The outer margin of the hypoechoic poloxamer is visualized upon injection into the celiac plexus (arrows).

Figure 4 Group 1 (A) and group 2 (B) at necropsy.