STAT-3 correlates with lymph node metastasis and cell survival in gastric cancer

Figure 1 Expression in the cytoplasm of gastric cancer tissues (× 400). A: Detection of signal transducer and activator of transcription-3 (STAT3) mRNA (in situ hybridization); B: STAT3 (IH); C: Phosphor-STAT3 (IH); D: Suppressor of cytokine signaling-1 (IH); E: Survivin (IH); F: Bcl-2 (IH).

Figure 2 Survival curve in 53 gastric cancer patients following curative resection according to the metastatic status of lymph nodes (A) and different expression levels of phosphor-signal transducer and activator of transcription-3 (B). A: Negative lymph node metastasis and positive lymph node metastasis; B: Negative and positive expression of pSTAT3.