Prognostic relevance of β-catenin expression in T2-3N0M0 esophageal squamous cell carcinoma

Figure 1 Expression of β-catenin in esophageal squamous cell carcinoma tissue samples (magnification × 400). A: Immunohistochemical staining of β-catenin in cytoplasm and membrane of cancer cells (immunohistochemistry score: 15); B: Immunohistochemical staining of β-catenin in cytoplasm of cancer cells (immunohistochemistry score: 3).

Figure 2 Receiver operating characteristic curve analysis of β-catenin and selection of cut-off score.

Figure 3 Kaplan-Meier survival curves for patients with esophageal squamous cell carcinoma at stage T2-3N0M0 according to β-catenin expression.

Figure 4 Kaplan-Meier survival curves for patients with esophageal squamous cell carcinoma according to β-catenin expression. A: Correlation between β-catenin expression and post-operative survival rate of patients with T2 lesions; B: Correlation between β-catenin expression and post-operative survival rate of patients with T3 lesions.

Figure 5 Kaplan-Meier survival curves for patients with esophageal squamous cell carcinoma stratified for pathological stage according to β-catenin expression. A: Correlation between β-catenin expression and post-operative survival rate of patients with IIA diseases; B: Correlation between β-catenin expression and post-operative survival rate of patients with IIB diseases.