Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization

Figure 1 Hybrid MR/IR suite at investigators’ institution. Moving table (arrow) allows the rapid transfer of patients between radiographic DSA and MRI during TACE. MRI: Magnetic resonance imaging; IR: Interventional radiology; DSA: Digital subtraction angiography; TACE: Transcatheter arterial chemoembolization.

Figure 2 Scatter-plot graph of 16 separately treated HCC lesions showing intra-procedural ADC percent change and their corresponding 1-mo EASL status. ADC: Apparent diffusion coefficient; HCC: Hepatocellular carcinoma; EASL: European Association for the Study of the Liver; CR: Complete response; PR: Partial response; PD: Progressive disease; SD: Stable disease.

Figure 3 Representative T1W, DW, and ADC MR images from a 70 year-old man with right-lobe HCC secondary to autoimmune hepatitis. Images were acquired before, immediately after, and 1 mo after TACE. Arrows on the anatomical images indicate tumor location with sample ROIs drawn on the functional MR images. Intra-procedural ADC changed by 28.6%, which predicted a favorable EASL response at 1 mo. T1W: T1-weighted; DW: Diffusion-weighted.