Silencing Fas-associated phosphatase 1 expression enhances efficiency of chemotherapy for colon carcinoma with oxaliplatin

Figure 1 Expression of Fas-associated phosphatase 1 (FAP-1) mRNA (A) and protein (B) after oxaliplation administration. Oxaliplatin promotes FAP-1 expression of SW480 cells at 0, 24, 48 and 72 h after chemotherapy. ^bP < 0.01 vs 0 h group.

Figure 2 Small interfering RNA (siRNA) silencing FAP-1 expression in siRNA 1709 group (A and C) and at the concentration of 60 nmol/L (B and D). ^bP < 0.01 vs 0 h group.

Figure 3 FAP-1 siRNA increasing the inhibitory effect of oxaliplatin on proliferation of SW480 cells.

Figure 4 FAP-1 siRNA enhancing the apoptosis inducing effect of oxaliplatin.