Dysregulation of apoptosis in hepatocellular carcinoma cells

Figure 1 Dysregulation of the TGF-β pathways in HCC cells favours its pro-tumorigenic activities. In red, molecules whose expression is down-regulated; in green, molecules either up-regulated or overactivated. See text for details.

Figure 2 Alterations in the expression or functions of death receptor pathways and apoptosis regulatory proteins in HCC cells. In red, proteins either down-regulated or inactivated; in green, proteins either up-regulated or overactivated. See text for details.

Figure 3 Overactivation of survival signals in HCC cells. In red, proteins either down-regulated or inactivated; in green, proteins either up-regulated or overactivated. See text for details.