Duodenal biopsy may be avoided when high transglutaminase antibody titers are present

Figure 1 Serum tTG antibody level vs patient age. An inverse relationship was observed for the levels of serum tTG antibody with increasing patient age.

Figure 2 Histopathological differences between children and adults according to Marsh classification.

Figure 3 Serum tTG antibody levels vs Marsh classification. tTG IgA was significantly correlated with Marsh type.

Figure 4 ROC showing the maximum area under the curve for Marsh type 3 histology at cut-off point of 30 U tTG antibody.

Figure 5 Follow-up of adult patients with an initial Marsh type 3 biopsy. Repeated biopsy showed persistent atrophy in 25% of the cases.