Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis

Figure 1 Ratios between angiotensins in healthy controls, and in patients with mild-to-moderate (MLD) and advanced liver disease (ALD). ^aP < 0.05 for the comparisons with the control group (Kruskal-Wallis followed by Dunn test for median comparisons). ^cP < 0.05 for the comparison between the MLD and ALD groups (Kruskal-Wallis followed by the Dunn test for median comparisons). Ang I: Angiotensin I; Ang II : Angiotensin II; Ang-(1-7): Angiotensin-(1-7).

Figure 2 Ratios between angiotensins in the peripheral and splanchnic circulations of liver transplanted patients during the pre-anhepatic stage of liver transplantation. ^aP < 0.05 for the comparison between the peripheral and splanchnic ratios (paired Student t-test). Ang I: Angiotensin I; Ang II: Angiotensin II; Ang-(1-7): Angiotensin-(1-7).

Figure 3 Correlations between Ang-(1-7)/Ang II ratios and CO and SVR. Correlation coefficients (r) and P values were calculated by Spearman’s test.