Resected case of eosinophilic cholangiopathy presenting with secondary sclerosing cholangitis

Figure 1 CT demonstrating dilatation of both the intrahepatic and extrahepatic bile ducts, diffuse thickening of the wall of the extrahepatic bile duct (arrow), and thickening of the gallbladder wall (arrowhead).

Figure 2 ERC showing an obstruction of the lower bile duct (arrow).

Figure 3 Histological examination of the bile duct wall. A: Conspicuous fibrosis was seen diffusely in the bile duct wall; B: Eosinophilic infiltration was very mild, and in some areas eosinophilic leukocytes were not seen; C: There were some areas with scattered eosinophilic leukocytes.

Figure 4 Histological examination showing marked eosinophilic infiltration in the gallbladder wall.

Figure 5 Liver biopsy showing mild portal fibrosis and concentric layers of fibrotic tissue surrounding the bile duct.