Diagnosis and management of microscopic colitis

Figure 1 Age- and sex-specific incidence of CC (A) and LC (B). Reprinted with permission from Gut 2004; 53: 346-350[5].

Figure 2 Biopsy from colon. A: normal colonic mucosa (H&E stain); B: typical findings of CC-increased subepithelial collagen layer, inflammation of lamina propria and epithelial cell damage with intraepithelial lymphocytes (Van Gieson's stain); C: typical findings of LC-epithelial cell damage with intraepithelial lymphocytes and inflammation in the lamina propria (H&E stain).

Figure 3 Tenascin immunostaining in CC.

Figure 4 Immunostaining of CD3+ T lymphocytes in LC.

Figure 5 Treatment algorithm for MC.