Gastrointestinal manifestations of systemic mastocytosis

Figure 1 The patient subsequently had maculopapular rashes which on biopsy showed increased numbers of dermal mast cells highlighted by c-kit (CD 117) immunoperoxidase staining consistent with that of dermal mastocytosis. The haematoxylin and eosin stain (HE) is also included.

Figure 2 On colonoscopy a mucus type material adherent to the mucosa was present in the right colon along with a slightly raised appearance of the mucosa through areas of the transverse and right colon.

Figure 3 The biopsy in these colonic regions showed an increased number of mast cells with recruited eosinophils in the lamina propria (HE).

Figure 4 The mast cells are highlighted by positive c-kit staining.