AIDS-associated plasmablastic lymphoma presenting as a poorly differentiated esophageal tumor: A diagnostic dilemma

Figure 1 CT scan of chest highlighting the large distal esophageal mass. Note the impressive constriction of the esophageal lumen (arrow).

Figure 2 Whole body PET scan demonstrates intensely increased metabolic activity corresponding to the large esophagogastric mass. There is also focal increased activity in a right iliac node.

Figure 3 Upper Endoscopic evaluation shows esophageal mass with ulcerative features which extended into the gastric fundus.

Figure 4 A: HE image shows a poorly differentiated, malignant neoplasm composed of irregular sheets of cells. Cells are cytologically atypical with somewhat eccentric vesicular nuclei and prominent nucleoli (× 40); B: Immunohistochemistry shows patchy but strong staining of tumor cells for CD138 (× 40).