Effect of antidepressants on body weight, ethology and tumor growth of human pancreatic carcinoma xenografts in nude mice

Figure 1 Effects of antidepressants on body weight of nude mice. Data are represented as mean ± SD. ^aP < 0.05, ^bP < 0.01 vs fluoxetine group, ^dP < 0.01 vs control group, ^fP < 0.01 vs control group.

Figure 2 Effects of antidepressants on food intake of mice. Data are represented as mean ± SD. ^bP < 0.01 vs fluoxetine group, ^dP < 0.01 vs control group, ^fP < 0.01 vs control group.

Figure 3 Horizontal (A), vertical (B) and grooming (C) activity in pancreatic tumor-bearing mice in the OFT. Data are represented as mean ± SD. ^bP < 0.01 vs fluoxetine group, ^dP < 0.01 vs control group, ^fP < 0.01 vs control group.

Figure 4 Effect of antidepressants on the growth of pancreatic cancer xenografts. Data are represented as mean ± SD.