Risk of colorectal neoplasm in patients with acromegaly: A meta-analysis

Figure 1 Flow diagram of the studies identified in this meta-analysis.

Figure 2 Forest plot showing individual and pooled ORs (95% CIs) and P values in studies comparing the colon adenoma prevalence in acromegaly patients and controls.

Figure 3 Funnel plot of selected studies examining colon adenoma prevalence in acromegaly patients and controls. No evidence of publication bias found (P = 0.711, by adjusted rank correlation test). Similarly no evidence of publication bias was found for the other colon neoplasias studied, i.e. colon hyperplastic polyps and colon cancer (see results, Table 2).

Figure 4 Forest plot showing individual and pooled ORs (95% CIs) and P values in studies comparing the colon hyperplastic polyp prevalence (A) and the colon cancer prevalence (B) in acromegaly patients and controls.