N-acetyl-L-cysteine combined with mesalamine in the treatment of ulcerative colitis: Randomized, placebo-controlled pilot study

Figure 1 Reduced glutathione levels in whole blood and tumor necrosis factor alpha (TNF-α), interleukin IL-6, IL-8, and monocyte chemoattractant protein (MCP)-1 levels in plasma of subjects after 4 wk of treatment with mesalamine plus NAC (Group A) or mesalamine plus placebo (Group B). mean ± SD. ^aP < 0.05 represent the significance level compared with basal values using the Student' t-test.