Current role of ultrasound for the management of hepatocellular carcinoma

Figure 1 Contrast-enhanced harmonic imaging with Sonazoid in focal nodular hyperplasia (FNH). The centrifugal blood flow appearance like “spoke-wheel sign” was clearly demonstrated in the center of the nodules (arrows).

Figure 2 Contrast-enhanced harmonic imaging with Sonazoid in small HCC (9. 8 mm, arrows). A: Early-phase image (22 s after the injection); B: Late-phase image (10 min after the injection). The early-phase image showed positive enhancement and the late-phase image showed negative enhancement in the nodule. These findings could easily diagnose this lesion as HCC.

Figure 3 Assessment of therapeutic response after PEI for HCC. A: Contrast-enhanced CT with dynamic study; B: Contrast-enhanced US (Advanced Dynamic Flow with Levovist). Contrast-enhanced CT showed enhancement appearance which needed additional treatment within the treated area (arrow), and contrast-enhanced US could demonstrate a similar finding. Arrow heads: Lipiodol.

Figure 4 Real-time three-dimensional imaging of HCC (contrast-enhanced LIVE 3D with Sonazoid, iu22, Philips). Abundant tumor vessels were dramatically demonstrated in the HCC nodule. (Arrows: HCC nodule).