Carcinosarcoma of the liver with mesenchymal differentiation

Figure 1 Magnetic resonance imaging showing hypointense areas in the right lobe of the liver on a T1-weighted image (A) and an inhomogeneously hyperintense mass on a T2-weighted image (B).

Figure 2 Needle biopsy showing a sarcomatous area consisting of interlacing bundles of atypical spindle cells [hematoxylin-eosin stain; magnification x 200 (A), x 100 (B)] and immunohistochemical staining showing positive α-SMA (C).

Figure 3 Gross appearance of hepatic tumor.

Figure 4 Spindle cells (A), pleomorphic areas (B), or hyalization (C) in leiomyosarcoma (hematoxylin-eosin stain; magnification x 160).

Figure 5 Cholangiocarcinoma focus (A) (hematoxylin-eosin stain; magnification x160), component surrounded by fibrosis (B) (hematoxylin-eosin stain; magnification x100), intimately mixed carcinomatous and sarcomatous components (C) (hematoxylin-eosin stain; magnification x 160).

Figure 6 Sarcomatous portion of the tumor consisting of undifferentiated (embryonal) sarcoma [hematoxylin-eosin stain; magnification x 25 (A, B), x 160 (C)].