Clinical significance of activity of ALT enzyme in patients with hepatitis C virus

Figure 1 Scatter diagram and regression line showing a significant positive relationship between duration of HCV infection and serum alanine aminotransferase (r = 0. 46, P < 0.01).

Figure 2 Scatter diagram and regression line showing a significant inverse relationship between viral load and serum alanine aminotransferase (r = -0. 33, P < 0.05).

Figure 3 Scatter diagram and regression line showing a significant positive relationship between the Histology Activity Index and serum alanine aminotransferase (r = 0. 44, P < 0.01).

Figure 4 ROC curve of serum ALT for discriminating female HCV patients from women without liver disease. The better cutoff value for ALT was at 22 IU/L, with sensitivity of 87.5% and specificity of 100% in identifying subjects without HCV infection.

Figure 5 ROC curve of serum ALT for discriminating male HCV patients from men without liver disease. The better cutoff value for ALT was at 23 IU/L, with sensitivity of 100% and specificity of 100% in identifying subjects without HCV infection.